The kidney plays a vital role in activating vitamin D so the human body can absorb calcium out of food/fluid via the gut. Patients with reduced kidney function suffer from a lack of active vitamin D, which causes low levels of calcium in the blood.

With less calcium in the blood, glands in the neck, called the parathyroid glands, produce a hormone (parathyroidhormone, PTH) to raise calcium levels in the blood. Persistent low levels of calcium can cause a disease called secondary hyperparathyroidism. The body reacts by taking calcium from the bones, which causes renal osteodystrophy (ROD). ROD is a potentially painful condition that can result in bone fracture.

Patients with severely reduced, or no kidney function, need renal replacement therapy, such as haemodialysis.

Treating conditions in nephrology
At LEO Pharma, we have 30 years of experience in helping patients with reduced kidney function. Our products exist in several formulations to ensure every patient receives optimal treatment.

On the market since 1978, LEO Pharma’s vitamin D analogue is a widely used product, administered to a large percentage of patients with reduced kidney function. A huge body of knowledge in clinical practice documents the use of our vitamin D analogue. 

LEO Pharma is dedicated to the optimal treatment of patients with reduced kidney function. That’s why we are focused on providing new products in nephrology.